Tearing and stretching of muscles leads to ankle sprain. There is pain and swelling in joints. The normal movements are affected and the sprain limits physical movement making it difficult to walk and move around. If you do any movement or physical activity in which the joint is twisted, sprain can be the result. Ligament injury is the main cause of this problem. Common activities that cause this problem are walking and running on rough surface. Accidents during weight lifting can also cause sprain. Sprain occurs on wearing high-heeled footwear. Home remedies are the best treatment for ankle sprain. The top 18 home remedies to get rid of sprained ankle are as follows.